Application of high pressure induced by water-freezing to the direct catalytic asymmetric three-component List- Barbas-Mannich reaction

被引：136

作者：

Hayashi, Y ^{[1
]}

Tsuboi, W

Shoji, M

Suzuki, N

机构：

[1] Tokyo Univ Sci, Fac Engn, Dept Ind Chem, Shinjuku Ku, Tokyo 1628601, Japan

[2] RIKEN, Wako, Saitama 3510198, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2003年 / 125卷 / 37期

关键词：

D O I：

10.1021/ja0372513

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

High pressure induced by water-freezing has been successfully applied to the direct catalytic asymmetric-three component List-Barbas-Mannich reaction, in which higher yield and better enantioselectivity can be realized than those from the reaction at room temperature under 0.1 MPa. Copyright © 2003 American Chemical Society.

引用

页码：11208 / 11209

页数：2

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