C-H Bond Arylations and Benzylations on Oxazol(in)es with a Palladium Catalyst of a Secondary Phosphine Oxide

被引：73

作者：

Ackermann, Lutz ^{[1
]}

Barfuesser, Sebastian ^{[1
]}

Kornhaass, Christoph ^{[1
]}

Kapdi, Anant R. ^{[1
]}

机构：

[1] Univ Gottingen, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany

来源：

ORGANIC LETTERS | 2011年 / 13卷 / 12期

关键词：

CROSS-COUPLING REACTIONS; CARBON-HYDROGEN BONDS; AZOLE N-OXIDES; DIRECT ALKYNYLATION; DIRECT ALKYLATION; HIGHLY EFFICIENT; ARYL CHLORIDES; ACTIVATION; HALIDES; HETEROCYCLES;

D O I：

10.1021/ol200986x

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An air-stable, well-defined palladium complex derived from secondary phosphine oxide (SPO) (1-Ad)(2)P(O)H enabled efficient C-H bond functionalizations with ample scope, which set the stage for direct arylations and benzylations of (benz)oxazoles, as well as unprecedented palladium-catalyzed C-H bond arylations on nonaromatic oxazolines.

引用

页码：3082 / 3085

页数：4

共 81 条

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