Direct arylations of electron-deficient (hetero)arenes with aryl or alkenyl tosylates and mesylates

被引：128

作者：

Ackermann, Lutz ^{[1
]}

Fenner, Sabine ^{[1
]}

机构：

[1] Georg August Univ, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 01期

关键词：

CATALYZED C-H; INTERMOLECULAR DIRECT ARYLATION; CROSS-COUPLING REACTIONS; PYRIDINE-N-OXIDES; SUZUKI-MIYAURA; BOND ACTIVATION; PALLADIUM; AZINE; FUNCTIONALIZATION; ARENES;

D O I：

10.1039/c0cc02360d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A palladium catalyst derived from the ligand X-Phos enabled generally applicable direct arylations of electron-deficient heteroarenes and arenes with aryl and alkenyl tosylates or mesylates.

引用

页码：430 / 432

页数：3

共 48 条

[1] Catalytic arylation reactions by C-H bond activation with aryl tosylates [J].

Ackermann, L ;

Althammer, A ;

Born, R .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (16) :2619-2622

[2]

Ackermann L, 2009, MODERN ARYLATION METHODS, P1

[3] Dehydrative Direct Arylations of Arenes with Phenols via Ruthenium-Catalyzed C-H and C-OH Bond Functionalizations [J].

Ackermann, Lutz ;

Mulzer, Michael .

ORGANIC LETTERS, 2008, 10 (21) :5043-5045

[4] Assisted ruthenium-catalyzed C-H bond activation: Carboxylic acids as cocatalysts for generally applicable direct arylations in apolar solvents [J].

Ackermann, Lutz ;

Vicente, Ruben ;

Althammer, Andreas .

ORGANIC LETTERS, 2008, 10 (11) :2299-2302

[5] Catalytic arylations with challenging substrates: From air-stable HASPO preligands to indole syntheses and C-H-bond functionalizations [J].

Ackermann, Lutz .

SYNLETT, 2007, (04) :507-526

[6] Air-stable PinP(O)H as preligand for palladium-catalyzed Kumada couplings of unactivated tosylates [J].

Ackermann, Lutz ;

Althammer, Andreas .

ORGANIC LETTERS, 2006, 8 (16) :3457-3460

[7] Ruthenium-Catalyzed Direct Arylations Through C-H Bond Cleavages [J].

Ackermann, Lutz ;

Vicente, Ruben .

C-H ACTIVATION, 2010, 292 :211-229

[8] Metal-catalyzed direct alkylations of (hetero)arenes via C-H bond cleavages with unactivated alkyl halides [J].

Ackermann, Lutz .

CHEMICAL COMMUNICATIONS, 2010, 46 (27) :4866-4877

[9] Kumada-Corriu Cross-Couplings with 2-Pyridyl Grignard Reagents [J].

Ackermann, Lutz ;

Potukuchi, Harish K. ;

Kapdi, Anant R. ;

Schulzke, Carola .

CHEMISTRY-A EUROPEAN JOURNAL, 2010, 16 (11) :3300-3303

[10] Palladium-Catalyzed Direct Arylations, Alkenylations, and Benzylations through C-H Bond Cleavages with Sulfamates or Phosphates as Electrophiles [J].

Ackermann, Lutz ;

Barfuesser, Sebastian ;

Pospech, Jola .

ORGANIC LETTERS, 2010, 12 (04) :724-726

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