Protein crystallization - is it rocket science?

被引:16
作者
DeLucas, LJ [1 ]
机构
[1] Univ Alabama Birmingham, Ctr Biophys Sci & Engn, Birmingham, AL 35294 USA
基金
美国国家航空航天局;
关键词
D O I
10.1016/S1359-6446(01)01838-4
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Fueled by initial space shuttle results, the National Aeronautics and Space Administration (NASA) has been supporting fundamental studies of macromolecular crystal growth since 1985. The majority of this research is directed at understanding the relationship between experimental variables and important crystal characteristics. The program has resulted in new methods and technology that will benefit the crystallography community's effort to meet the ever-increasing demand for protein structural information. Microgravity crystallization results indicate a potential impact on structural biology's more challenging problems, as soon as long-duration experiments can be performed on the International Space Station.
引用
收藏
页码:734 / 744
页数:11
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