Technology for microarray analysis of gene expression

被引:101
作者
Watson, A [1 ]
Mazumder, A [1 ]
Stewart, M [1 ]
Balasubramanian, S [1 ]
机构
[1] Axys Pharmaceut, La Jolla, CA 92014 USA
关键词
D O I
10.1016/S0958-1669(98)80138-9
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The past year has demonstrated the versatility of microarrays for the analysis of whole model-organism genomes and has seen the development bf chips to measure the expression of 40,000 human genes. Microarray technology has also become considerably more robust and sensitive. Technology enhancements include the use of noncontact printing methods, improved 2-color sample preparation, and statistically based software for data analysis.
引用
收藏
页码:609 / 614
页数:6
相关论文
共 55 条
  • [41] Parallel human genome analysis: Microarray-based expression monitoring of 1000 genes
    Schena, M
    Shalon, D
    Heller, R
    Chai, A
    Brown, PO
    Davis, RW
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (20) : 10614 - 10619
  • [42] Steric factors influencing hybridisation of nucleic acids to oligonucleotide arrays
    Shchepinov, MS
    CaseGreen, SC
    Southern, EM
    [J]. NUCLEIC ACIDS RESEARCH, 1997, 25 (06) : 1155 - 1161
  • [43] Rapid determination of single base mismatch mutations in DNA hybrids by direct electric field control
    Sosnowski, RG
    Tu, E
    Butler, WF
    OConnell, JP
    Heller, MJ
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (04) : 1119 - 1123
  • [44] SOUTHERN E, 1997, Patent No. 5667667
  • [45] SOUTHERN E, 1997, Patent No. 5700637
  • [46] ARRAYS OF COMPLEMENTARY OLIGONUCLEOTIDES FOR ANALYZING THE HYBRIDIZATION BEHAVIOR OF NUCLEIC-ACIDS
    SOUTHERN, EM
    CASEGREEN, SC
    ELDER, JK
    JOHNSON, M
    MIR, KU
    WANG, L
    WILLIAMS, JC
    [J]. NUCLEIC ACIDS RESEARCH, 1994, 22 (08) : 1368 - 1373
  • [47] REAL-TIME DETECTION OF DNA HYBRIDIZATION AND MELTING ON OLIGONUCLEOTIDE ARRAYS BY USING OPTICAL-WAVE GUIDES
    STIMPSON, DI
    HOIJER, JV
    HSIEH, WT
    JOU, C
    GORDON, J
    THERIAULT, T
    GAMBLE, R
    BALDESCHWIELER, JD
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (14) : 6379 - 6383
  • [48] In situ surface plasmon resonance imaging detection of DNA hybridization to oligonucleotide arrays on gold surfaces
    Thiel, AJ
    Frutos, AG
    Jordan, CE
    Corn, RM
    Smith, LM
    [J]. ANALYTICAL CHEMISTRY, 1997, 69 (24) : 4948 - 4956
  • [49] Combining the preparation of oligonucleotide arrays and synthesis of high-quality primers
    Weiler, J
    Hoheisel, JD
    [J]. ANALYTICAL BIOCHEMISTRY, 1996, 243 (02) : 218 - 227
  • [50] Detection of differentially expressed genes in primary tumor tissues using representational differences analysis coupled to microarray hybridization
    Welford, SM
    Gregg, J
    Chen, E
    Garrison, D
    Sorensen, PH
    Denny, CT
    Nelson, SF
    [J]. NUCLEIC ACIDS RESEARCH, 1998, 26 (12) : 3059 - 3065