Asymmetric direct aldol reaction catalyzed by an L-prolinamide derivative: considerable improvement of the catalytic efficiency in the ionic liquid

被引：106

作者：

Guo, HM

Cun, LF

Gong, LZ ^{[1
]}

Mi, AQ

Jiang, YZ

机构：

[1] Chinese Acad Sci, Chengdu Inst Organ Chem, Key Lab Asymmetr Synth & Chirotechnol Sichuan Pro, Chengdu 610041, Peoples R China

[2] Chinese Acad Sci, Chengdu Inst Organ Chem, Union Lab Asymmetr Synth, Chengdu 610041, Peoples R China

[3] Chinese Acad Sci, Grad Sch, Beijing, Peoples R China

[4] Henan Normal Univ, Dept Chem, Xinxiang 453002, Henan, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2005年 / 11期

关键词：

D O I：

10.1039/b417267a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The asymmetric direct aldol reactions of a wide scope of aldehydes with unmodified ketones in the presence of 20 mol% (S, S, S)-pyrrolidine-2-carboxylic acid (2'-hydroxyl-1',2'-diphenylethyl)- amine ( 1) were performed in ionic liquids; aldol products with 91 to >99% ees for aromatic aldehydes and 99% ees for alphatic aldehydes were offered by the present procedure.

引用

页码：1450 / 1452

页数：3

共 30 条

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