学术探索
学术期刊
新闻热点
数据分析
智能评审

Enantioselective conjugate addition of diethylzinc to enones catalyzed by a copper complex of chiral aryl diphosphite

被引：106
作者：
Yan, M
Yang, LW
Wong, KY
Chan, ASC [1 ]
机构：
[1] Hong Kong Polytech Univ, Union Lab Asymmetr Synth, Hong Kong, Peoples R China
[2] Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Hong Kong, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 1999年 / 01期
关键词：
D O I：
10.1039/a807997h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The 1,4-conjugate addition of diethylzinc to cyclohex-2-enone and cyclopent-2-enone catalyzed by a copper complex of a chiral aryl diphosphite gave the desired products with 90.2 and 76.6% ee respectively.
引用
收藏
页码：11 / 12
页数：2
相关论文
共 24 条
  • [1] Asymmetric conjugate addition of diethyl zinc to enones with tartrate chiral phosphite ligands
    Alexakis, A
    Vastra, J
    Burton, J
    Mangeney, P
    [J]. TETRAHEDRON-ASYMMETRY, 1997, 8 (19) : 3193 - 3196
  • [2] Asymmetric conjugate addition of diethyl zinc to enones with chiral phosphine ligands
    Alexakis, A
    Burton, J
    Vastra, J
    Mangeney, P
    [J]. TETRAHEDRON-ASYMMETRY, 1997, 8 (24) : 3987 - 3990
  • [3] CHIRAL ARYL DIPHOSPHITES - A NEW CLASS OF LIGANDS FOR HYDROCYANATION CATALYSIS
    BAKER, MJ
    PRINGLE, PG
    [J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1991, (18) : 1292 - 1293
  • [4] (+)-camphor-derived tri- and tetradentate amino alcohols; synthesis and application as ligands in the nickel catalyzed enantioselective conjugate addition of diethylzinc
    deVries, AHM
    Imbos, R
    Feringa, BL
    [J]. TETRAHEDRON-ASYMMETRY, 1997, 8 (09) : 1467 - 1473
  • [5] Enantioselective conjugate addition of dialkylzinc reagents to cyclic and acyclic enones catalyzed by chiral copper complexes of new phosphorus amidites
    deVries, AHM
    Meetsma, A
    Feringa, BL
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1996, 35 (20): : 2374 - 2376
  • [6] Enantioselective conjugate addition of diethylzinc to chalcone catalyzed by Co(acac)(2) and chiral amino alcohols
    deVries, AHM
    Feringa, BL
    [J]. TETRAHEDRON-ASYMMETRY, 1997, 8 (09) : 1377 - 1378
  • [7] ASYMMETRIC INDUCTION IN THE CONJUGATE ADDITION-REACTIONS OF CHIRAL ORGANO(HETERO)CUPRATES
    DIETER, RK
    TOKLES, M
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1987, 109 (07) : 2040 - 2046
  • [8] Doyle M. P., 1995, ADV CATALYTIC PROCES, V1
  • [9] Highly enantioselective catalytic conjugate addition and tandem conjugate addition - Aldol reactions of organozinc reagents
    Feringa, BL
    Pineschi, M
    Arnold, LA
    Imbos, R
    de Vries, AHM
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1997, 36 (23) : 2620 - 2623
  • [10] Catalytic enantioselective conjugate additions using enantiopure beta-amino disulfides and beta-amino thiolates
    Gibson, CL
    [J]. TETRAHEDRON-ASYMMETRY, 1996, 7 (12) : 3357 - 3358
123