Synthesis and water solubility of adamantyl-OEG-fullerene hybrids

被引:25
作者
Bar-Shir, A [1 ]
Engel, Y [1 ]
Gozin, M [1 ]
机构
[1] Tel Aviv Univ, Raymond & Beverly Sackler Fac Exact Sci, Sch Chem, IL-69978 Tel Aviv, Israel
关键词
D O I
10.1021/jo0479359
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A series of new adamantyl-oligoethyleneglycol-fullerene hybrids was prepared via Bingel-Hirsch functionalization of the C-60 fullerene with various adamantyl-oligoethyleneglycol malonates. As NMDA-targeted antioxidants, these compounds may have the potential to be developed as therapeutic agents for the treatment of neurological disorders.
引用
收藏
页码:2660 / 2666
页数:7
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