A supramolecular approach to the preparation of charge-tunable dendritic polycations for efficient gene delivery

被引：91

作者：

Dong, Ruijiao ^{[1
]}

Zhou, Linzhu ^{[1
]}

Wu, Jieli ^{[2
]}

Tu, Chunlai ^{[1
]}

Su, Yue ^{[1
]}

Zhu, Bangshang ^{[2
]}

Gu, Hongchen ^{[3
]}

Yan, Deyue ^{[1
]}

Zhu, Xinyuan ^{[1
,2
]}

机构：

[1] Shanghai Jiao Tong Univ, Sch Chem & Chem Engn, State Key Lab Met Matrix Composites, Shanghai 200240, Peoples R China

[2] Shanghai Jiao Tong Univ, Instrumental Anal Ctr, Shanghai 200240, Peoples R China

[3] Shanghai Jiao Tong Univ, Med X Res Inst, Shanghai 200240, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 19期

基金：

中国国家自然科学基金;

关键词：

HYPERBRANCHED POLYMERS; MOLECULAR ARCHITECTURE; DENDRIMERS; POLYROTAXANES; TRANSFECTION; VECTORS; PEPTIDE; DRUG;

D O I：

10.1039/c1cc10934k

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

A facile supramolecular approach for the preparation of charge-tunable dendritic polycations, by a combination of the multi-functionality of dendritic polymers with the dynamic-tunable ability of supramolecular polymers, has been developed. It provides a new strategy for designing and developing efficient gene vectors via noncovalent interactions.

引用

收藏

页码：5473 / 5475

页数：3

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