Hemoglobin based hydrogen peroxide biosensor tuned by the photovoltaic effect of nano titanium dioxide

被引:108
作者
Zhou, H
Gan, X
Wang, J
Zhu, XL
Li, GX [1 ]
机构
[1] Nanjing Univ, Dept Biochem, Nanjing 210093, Peoples R China
[2] Nanjing Univ, Natl Key Lab Pharmaceut Biotechnol, Nanjing 210093, Peoples R China
关键词
D O I
10.1021/ac050924a
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The photovoltaic effect of titanium dioxide (TiO2) nanoparticles, induced by ultraviolet light, can greatly improve the catalytic activity of hemoglobin as a peroxidase, with the sensitivity increased nearly 3-fold and the detection limit lowered 2 orders, in contrast to the catalytic reactions in the dark, which indicates a possible method to tune the properties of proteins for development of photo controlled protein-based biosensors.
引用
收藏
页码:6102 / 6104
页数:3
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