A Two-Component Small Molecule System for Activity-Based Detection and Signal Amplification: Application to the Visual Detection of Threshold Levels of Pd(II)

被引：111

作者：

Baker, Matthew S. ^{[1
]}

Phillips, Scott T. ^{[1
]}

机构：

[1] Penn State Univ, Dept Chem, University Pk, PA 16802 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2011年 / 133卷 / 14期

关键词：

PALLADIUM; CATALYSIS; CHEMODOSIMETER; FLUORIDE; SENSOR;

D O I：

10.1021/ja108347d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A detection and signal amplification strategy aimed toward threshold diagnostic assays for use in resource-limited settings is described. The strategy employs two small molecule reagents that work in tandem. One reagent detects a specific analyte, while the second amplifies a colorimetric readout autocatalytically. The strategy is demonstrated using palladium(II) as a model analyte.

引用

页码：5170 / 5173

页数：4

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