Solid-phase oligosaccharide synthesis and combinatorial carbohydrate libraries

被引：412

作者：

Seeberger, PH ^{[1
]}

Haase, WC ^{[1
]}

机构：

[1] MIT, Dept Chem, Cambridge, MA 02139 USA

来源：

CHEMICAL REVIEWS | 2000年 / 100卷 / 12期

关键词：

D O I：

10.1021/cr9903104

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This review covers the central issues of carbohydrate chemistry. Efforts to apply different glycosylating agents to the assembly of oligosaccharides on a polymer matrix are highlighted, followed by a description of on-resin analytical methods. A comparison of the currently available methods and the prospects for the development of an automated solid-phase oligosaccharide synthesizer are discussed.

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页码：4349 / +

页数：46

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