An array of possibilities for the study of autoimmunity

被引：69

作者：

Fathman, CG ^{[1
]}

Soares, L

Chan, SM

Utz, PJ

机构：

[1] Stanford Univ, Sch Med, Dept Med, Div Rheumatol & Immunol, Stanford, CA 94305 USA

[2] IBMP, Curitiba, Parana, Brazil

来源：

NATURE | 2005年 / 435卷 / 7042期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1038/nature03726

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Since the completion of the sequencing of the human genome, scientific focus has shifted from studying genes to analysing the much larger number of proteins encoded by them. Several proteins can be generated from a single gene depending on how the genetic information is read ( transcribed) and how the resultant protein is modified following translation (post-translational modification). Genomic and proteomic technologies are already providing useful information about autoimmune disease, and they are likely to lead to important discoveries within the next decade.

引用

页码：605 / 611

页数：7

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