Carbon-13 labelling strategy for studying the ATP metabolism in individual yeast cells by micro-arrays for mass spectrometry

被引：31

作者：

Urban, Pawel L. ^{[1
,2
]}

Schmidt, A. Mareike ^{[3
]}

Fagerer, Stephan R. ^{[1
]}

Amantonico, Andrea ^{[1
]}

Ibanez, Alfredo ^{[1
]}

Jefimovs, Konstantins ^{[4
]}

Heinemann, Matthias ^{[3
,5
]}

Zenobi, Renato ^{[1
]}

机构：

[1] ETH, Dept Chem & Appl Biosci, CH-8093 Zurich, Switzerland

[2] Natl Chiao Tung Univ, Dept Appl Chem, Hsinchu 300, Taiwan

[3] ETH, Inst Mol Syst Biol, CH-8093 Zurich, Switzerland

[4] Swiss Fed Labs Mat Sci & Technol, Lab Elect Metrol Reliabil, EMPA, CH-8600 Dubendorf, Switzerland

[5] Univ Groningen, Groningen Biomol Sci & Biotechnol Inst, NL-9747 AG Groningen, Netherlands

来源：

MOLECULAR BIOSYSTEMS | 2011年 / 7卷 / 10期

基金：

瑞士国家科学基金会;

关键词：

MALDI-MS; SINGLE; HETEROGENEITY;

D O I：

10.1039/c1mb05248a

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Isotopic labelling of cellular metabolites, used in conjunction with high-density micro-arrays for mass spectrometry enables observation of ATP metabolism in single yeast cells.

引用

页码：2837 / 2840

页数：4

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