The effects of tomato consumption on serum glucose, apolipoprotein B, apolipoprotein A-I, homocysteine and blood pressure in type 2 diabetic patients

被引:55
作者
Shidfar, Farzad [1 ]
Froghifar, Neda [1 ]
Vafa, Mohammadreza [1 ]
Rajab, Asadolah [2 ]
Hosseini, Sharieh [3 ]
Shidfar, Shahrzad [4 ]
Gohari, Mahmoodreza [5 ]
机构
[1] Iran Univ Med Sci, Sch Hlth, Dept Nutr, Tehran 1449614525, Iran
[2] Iranian Diabet Assoc, Tehran, Iran
[3] Islamic Azad Univ, Sari Branch, Sari, Iran
[4] Univ Massachusetts, Worcester Mem Hosp, Worcester, MA 01605 USA
[5] Iran Univ Med Sci, Sch Management & Med Informat, Tehran 1449614525, Iran
关键词
Homocysteine; apolipoprotein B; apolipoprotein A-I; tomato; blood pressure; type; 2; diabetes; HIGH-DENSITY-LIPOPROTEIN; CORONARY-HEART-DISEASE; LIPID PROFILE; NATURAL ANTIOXIDANTS; HDL CHOLESTEROL; WEIGHT-LOSS; LYCOPENE; EXTRACT; RISK; PRODUCTS;
D O I
10.3109/09637486.2010.529072
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Tomatoes are a rich source of lycopene, beta-carotene, potassium, vitamin C, flavonoids, folate and vitamin E that may provide protection against the development of type 2 diabetic patients, so the present study was undertaken to evaluate the effects of tomato intake on serum glucose, homocysteine, apolipoprotein (apo) B, apoA-I and blood pressure in type 2 diabetic patients. In a quasi-experimental study, 32 type 2 diabetes patients received 200 g raw tomato daily for 8 weeks. Serum glucose enzymatically, apoB and apoA-I immunoturbidometrically and homocysteine by high-performance liquid chromatography were measured at the beginning and end of 8 weeks. There were significant decreases in systolic and diastolic blood pressure and also a significant increase in apoA-I at the end of study compared with initial values (P = 0.0001, P = 0.0001 and P = 0.013, respectively). In conclusion, 200 g raw tomato per day had a favored effect on blood pressure and apoA-I so it might be beneficial for reducing cardiovascular risk associated with type 2 diabetes.
引用
收藏
页码:289 / 294
页数:6
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