ISACGH:: a web-based environment for the analysis of array CGH and gene expression which includes functional profiling

被引：23

作者：

Conde, Lucia ^{[1
]}

Montaner, David ^{[1
,2
]}

Burguet-Castell, Jordi ^{[1
]}

Tarraga, Joaquin ^{[1
,2
]}

Medina, Ignacio ^{[1
]}

Al-Shahrour, Fatima ^{[1
]}

Dopazo, Joaquin ^{[1
,2
]}

机构：

[1] CIPF, Bioinformat Dept, Valencia 46013, Spain

[2] CIPF, INB, Valencia 46013, Spain

来源：

NUCLEIC ACIDS RESEARCH | 2007年 / 35卷

关键词：

D O I：

10.1093/nar/gkm257

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We present the ISACGH, a web-based system that allows for the combination of genomic data with gene expression values and provides different options for functional profiling of the regions found. Several visualization options offer a convenient representation of the results. Different efficient methods for accurate estimation of genomic copy number from array-CGH hybridization data have been included in the program. Moreover, the connection to the gene expression analysis package GEPAS allows the use of different facilities for data pre-processing and analysis. A DAS server allows exporting the results to the Ensembl viewer where contextual genomic information can be obtained. The program is freely available at: http://isacgh.bioinfo.cipf.es or within http://www.gepas.org.

引用

页码：W81 / W85

页数：5

共 28 条

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