Antifungal Susceptibility Profile of Human-Pathogenic Species of Lichtheimia

被引：25

作者：

Alastruey-Izquierdo, Ana ^{[1
]}

Cuesta, Isabel ^{[1
]}

Walther, Grit ^{[2
]}

Cuenca-Estrella, Manuel ^{[1
]}

Rodriguez-Tudela, Juan Luis ^{[1
]}

机构：

[1] Inst Salud Carlos III, Ctr Nacl Microbiol, Serv Micol, Majadahonda 28220, Spain

[2] CBS KNAW Fungal Biodivers Ctr, Utrecht, Netherlands

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2010年 / 54卷 / 07期

关键词：

IN-VITRO SUSCEPTIBILITY; INOCULUM PREPARATION; SALVAGE THERAPY; POSACONAZOLE; ZYGOMYCOSIS; ASPERGILLUS; MUCORALES; STRAINS; AGENTS;

D O I：

10.1128/AAC.01270-09

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Forty-four isolates belonging to human pathogenic species of Lichtheimia were tested against nine antifungal agents by using the EUCAST methodology. No remarkable differences were found between the clinical species, although L. ramosa showed slightly higher MICs for all drugs. Amphotericin B was the most active drug. Among azole drugs, posaconazole had the best activity in vitro and voriconazole was inactive. Echinocandins showed activity for some isolates, suggesting a potential role in combination therapy.

引用

页码：3058 / 3060

页数：3

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