New halimane diterpenoids from Croton oblongifolius

被引：22

作者：

Roengsumran, S ^{[1
]}

Pornpakakul, S

Muangsin, N

Sangvanich, P

Nhujak, T

Singtothong, P

Chaichit, N

Puthong, S

Petsom, A

机构：

[1] Chulalongkorn Univ, Fac Sci, Dept Chem, Res Ctr Bioorgan Chem, Bangkok 10330, Thailand

[2] Thammasat Univ, Fac Sci & Technol, Dept Phys, Pathum Thani, Thailand

[3] Chulalongkorn Univ, Inst Biotechnol & Genet Engn, Bangkok, Thailand

来源：

PLANTA MEDICA | 2004年 / 70卷 / 01期

关键词：

D O I：

10.1055/s-2004-815466

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three new halimane-type diterpenoids, crotohalimaneic acid (1), crotohalimoneic acid (2) and 12-benzoyloxycrotohalimaneic acid (3), were isolated from the stem bark of Croton oblongifolius Roxb. Their structures were established on the basis of spectroscopic and X-ray analysis. Compounds 1 and 2 showed non-specific strong cytotoxicity against a panel of human tumor cell lines; whereas 3 was inactive.

引用

页码：87 / 89

页数：3

共 13 条

[1] Sesquiterpenoids and diterpenoids from the liverwort Jungermannia truncata [J].

Buchanan, MS ;

Connolly, JD ;

Kadir, AA ;

Rycroft, DS .

PHYTOCHEMISTRY, 1996, 42 (06) :1641-1646

[2] Diterpenoids and flavonoids from Ophryosporus charrua [J].

Favier, LS ;

Nieto, M ;

Giordano, OS ;

Tonn, CE .

PHYTOCHEMISTRY, 1997, 45 (07) :1469-1474

[3] CLERODANE AND ENT-HALIMANE DITERPENES FROM POLYALTHIA-LONGIFOLIA [J].

HARA, N ;

ASAKI, H ;

FUJIMOTO, Y ;

GUPTA, YK ;

SINGH, AK ;

SAHAI, M .

PHYTOCHEMISTRY, 1995, 38 (01) :189-194

[4] CLERODANE-TYPE AND HALIMANE-TYPE DITERPENOIDS FROM THE LIVERWORT JUNGERMANNIA-HYALINA [J].

NAGASHIMA, F ;

TANAKA, H ;

KAN, Y ;

HUNECK, S ;

ASAKAWA, Y .

PHYTOCHEMISTRY, 1995, 40 (01) :209-212

[5]

Ngamrojnavanich N, 2003, PLANTA MED, V69, P555, DOI 10.1055/s-2003-40636

[6] Hydroxylated diterpenoids from Halimium viscosum [J].

Rodilla, JML ;

De Mendonça, DIM ;

Urones, JG ;

Moro, RF .

PHYTOCHEMISTRY, 1998, 49 (03) :817-822

[7] Croblongifolin, a new anticancer clerodane from Croton oblongifolius [J].

Roengsumran, S ;

Musikul, K ;

Petsom, A ;

Vilaivan, T ;

Sangvanich, P ;

Pornpakakul, S ;

Puthong, S ;

Chaichantipyuth, C ;

Jaiboon, N ;

Chaichit, N .

PLANTA MEDICA, 2002, 68 (03) :274-277

[8] Two new cembranoids from Croton oblongifolius [J].

Roengsumran, S ;

Achayindee, S ;

Petsom, A ;

Pudhom, K ;

Singtothong, P ;

Surachetapan, C ;

Vilaivan, T .

JOURNAL OF NATURAL PRODUCTS, 1998, 61 (05) :652-654

[9] Labdane diterpenoids from Croton oblongifolius [J].

Roengsumran, S ;

Petsom, A ;

Sommit, D ;

Vilaivan, T .

PHYTOCHEMISTRY, 1999, 50 (03) :449-453

[10] Cytotoxic labdane diterpenoids from Croton oblongifolius [J].

Roengsumran, S ;

Petsom, A ;

Kuptiyanuwat, N ;

Vilaivan, T ;

Ngamrojnavanich, N ;

Chaichantipyuth, C ;

Phuthong, S .

PHYTOCHEMISTRY, 2001, 56 (01) :103-107

← 1 2 →