Control of gene expression in Plasmodium falciparum

被引：86

作者：

Horrocks, P

Dechering, K

Lanzer, M

机构：

[1] Univ Wurzburg, Zentrum Infekt Forsch, D-97070 Wurzburg, Germany

[2] Univ Nijmegen, Dept Mol Biol, NL-6525 ED Nijmegen, Netherlands

来源：

MOLECULAR AND BIOCHEMICAL PARASITOLOGY | 1998年 / 95卷 / 02期

关键词：

gene expression; Plasmodium falciparum; promoter;

D O I：

10.1016/S0166-6851(98)00110-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Transfection has facilitated a functional analysis of transcriptional processes in the human malarial parasite Plasmodium falciparum, providing the first fascinating glimpses into the mechanisms regulating parasite development and pathogenicity. Here we review our rapidly evolving knowledge of what constitutes a promoter, what factors regulate promoter activity and how this activity affects the manifestation of the disease. (C) 1998 Elsevier Science B.V. All rights reserved.

引用

收藏

页码：171 / 181

页数：11

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