The incidence of tonsillar cancer in Sweden is increasing

被引:114
作者
Hammarstedt, Lalle
Dahlstrand, Hanna
Lindquist, David
, Liselotte Onelov
Ryott, Michael
Luo, Juhua
Dalianis, Tina
Ye, Weimin
Munck-Wikland, Eva
机构
[1] Karolinska Univ Hosp, Dept Otorhinolaryngol Head & Neck Surg, S-17176 Stockholm, Sweden
[2] Karolinska Univ Hosp, Dept Oncol Pathol, S-17176 Stockholm, Sweden
[3] Karolinska Univ Hosp, Dept Epidemiol & Biostat, S-17176 Stockholm, Sweden
关键词
tonsillar cancer; head and neck cancer; incidence; squamous cell carcinoma; human papilloma virus;
D O I
10.1080/00016480601110170
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Conclusions. The incidence of tonsillar cancer in Sweden is increasing, particularly among men. Risk factors other than smoking may have contributed to the observed secular trend in men. In women, however, smoking can be a part of the explanation. Further studies to look at changes in other environmental factors, such as human papilloma virus (HPV) infection, are clearly warranted. Objectives. Head and neck cancer is related to smoking habits and smoking has decreased substantially during the last 30 years in Sweden. However, there is suspicion that the incidence of tonsillar cancer has increased in the last 30 years as it has in the USA and Finland, in spite of reduced prevalence of known risk factors. The time trends of oral and oropharygeal cancer have been studied in Sweden, but not tonsillar cancer specifically. Subjects and methods. We used the Swedish Cancer Registry to assess the secular trend of incidence of tonsillar cancer in Sweden since 1960. For comparison we investigated the incidence of other oral cancers and lung cancer, which are also smoking-related. The prevalence of smoking was investigated for reference. Age-standardized incidence rates were calculated and linear regression was used to evaluate secular trends. Results. The incidence of tonsillar cancer increased by 2.6% per year in men and 1.1% in women. No similar increase was seen in the other oral cancers. For lung cancer there was a decrease in the incidence in men, but in women the incidence is still increasing.
引用
收藏
页码:988 / 992
页数:5
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