Grignard-Type Arylation of Aldehydes via a Rhodium-Catalyzed C-H Activation under Mild Conditions

被引：130

作者：

Yang, Luo ^{[1
]}

Correia, Camille A. ^{[1
]}

Li, Chao-Jun ^{[1
]}

机构：

[1] McGill Univ, Dept Chem, Montreal, PQ H3A 2K6, Canada

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2011年 / 353卷 / 08期

基金：

加拿大自然科学与工程研究理事会;

关键词：

aldehydes; arylation; C-H activation; Grignard-type reaction; rhodium catalysis; BOND FORMATION; FUNCTIONALIZATION; CARBON; AIR;

D O I：

10.1002/adsc.201100232

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

An efficient Grignard-type arylation of aldehydes via aryl C-H activation was achieved under mild conditions catalyzed by rhodium. The reaction provides an easy access to a wide variety of benzyl alcohols and can tolerate various functional groups as well as air and water.

引用

页码：1269 / 1273

页数：5

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