Complementary emerging techniques: high-resolution PET and MRI

被引:64
作者
Jacobs, RE [1 ]
Cherry, SR
机构
[1] CALTECH, Beckman Inst, Biol Imaging Ctr, Pasadena, CA 91125 USA
[2] Univ Calif Davis, Dept Biomed Engn, Davis, CA 95616 USA
关键词
D O I
10.1016/S0959-4388(00)00259-2
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Noninvasive imaging technologies provide a unique window on the anatomy, physiology and function of living organisms. Imaging systems and methods have been developed for the study of small animal model systems that offer exciting new possibilities in neuroscience. Advances in magnetic resonance microscopy and positron emission tomography, and their applications in brain imaging, have provided many benefits to neurobiology, ranging from detailed in vivo neuroanatomy to the measurement of specific molecular targets.
引用
收藏
页码:621 / 629
页数:9
相关论文
共 64 条
[31]   Brain studies of mouse models for neurogenetic disorders using in vivo magnetic resonance imaging (MRI) [J].
Kooy, RF ;
Verhoye, M ;
Lemmon, V ;
Van Der Linden, A .
EUROPEAN JOURNAL OF HUMAN GENETICS, 2001, 9 (03) :153-159
[32]   In vivo imaging of neuronal activation and plasticity in the rat brain by high resolution positron emission tomography (microPET) [J].
Kornblum, HI ;
Araujo, DM ;
Annala, AJ ;
Tatsukawa, KJ ;
Phelps, ME ;
Cherry, SR .
NATURE BIOTECHNOLOGY, 2000, 18 (06) :655-660
[33]   Positron emission tomography for quantitative determination of glucose metabolism in normal and ischemic brains in rats: An insoluble problem by the Harderian glands [J].
Kuge, Y ;
Minematsu, K ;
Hasegawa, Y ;
Yamaguchi, T ;
Mori, H ;
Matsuura, H ;
Hashimoto, N ;
Miyake, Y .
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 1997, 17 (01) :116-120
[34]   Initial results from the Sherbrooke avalanche photodiode positron tomograph [J].
Lecomte, R ;
Cadorette, J ;
Rodrigue, S ;
Lapointe, D ;
Rouleau, D ;
Bentourkia, M ;
Yao, R ;
Msaki, P .
IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1996, 43 (03) :1952-1957
[35]   Virtual neuropathology: Three-dimensional visualization of lesions due to toxic insult [J].
Lester, DS ;
Pine, PS ;
Delnomdedieu, M ;
Johannessen, JN ;
Johnson, GA .
TOXICOLOGIC PATHOLOGY, 2000, 28 (01) :100-104
[36]   Development of a depth of interaction detector for γ-rays [J].
Liu, H ;
Omura, T ;
Watanabe, M ;
Yamashita, T .
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2001, 459 (1-2) :182-190
[37]   In vivo visualization of gene expression using magnetic resonance imaging [J].
Louie, AY ;
Hüber, MM ;
Ahrens, ET ;
Rothbächer, U ;
Moats, R ;
Jacobs, RE ;
Fraser, SE ;
Meade, TJ .
NATURE BIOTECHNOLOGY, 2000, 18 (03) :321-325
[38]  
Matalon R, 2000, J GENE MED, V2, P165
[39]   Quantitative assessment of longitudinal metabolic changes in vivo after traumatic brain injury in the adult rat using FDG-MicroPET [J].
Moore, AH ;
Osteen, CL ;
Chatziioannou, AF ;
Hovda, DA ;
Cherry, SR .
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2000, 20 (10) :1492-1501
[40]   Diffusion tensor imaging of the developing mouse brain [J].
Mori, S ;
Itoh, R ;
Zhang, JY ;
Kaufmann, WE ;
van Zijl, PCM ;
Solaiyappan, M ;
Yarowsky, P .
MAGNETIC RESONANCE IN MEDICINE, 2001, 46 (01) :18-23