FTY720: Altered lymphocyte traffic results in allograft protection.

被引：151

作者：

Brinkmann, V

Pinschewer, DD

Feng, L

Chen, S

机构：

[1] Novartis Pharma AG, Transplantat Res, CH-4002 Basel, Switzerland

[2] Univ Zurich, Inst Expt Immunol, CH-8091 Zurich, Switzerland

[3] Scripps Res Inst, La Jolla, CA 92037 USA

来源：

TRANSPLANTATION | 2001年 / 72卷 / 05期

关键词：

D O I：

10.1097/00007890-200109150-00002

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

[No abstract available]

引用

页码：764 / 769

页数：6

共 52 条

[1] DESIGN, SYNTHESIS, AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF 2-SUBSTITUTED-2-AMINO-1,3-PROPANEDIOLS - DISCOVERY OF A NOVEL IMMUNOSUPPRESSANT, FTY720 [J].

ADACHI, K ;

KOHARA, T ;

NAKAO, N ;

ARITA, M ;

CHIBA, K ;

MISHINA, T ;

SASAKI, S ;

FUJITA, T .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1995, 5 (08) :853-856

[2] FTY720: a novel transplantation drug that modulates lymphocyte traffic rather than activation [J].

Brinkmann, V ;

Pinschewer, D ;

Chiba, K ;

Feng, LL .

TRENDS IN PHARMACOLOGICAL SCIENCES, 2000, 21 (02) :49-52

[3] FTY720 alters lymphocyte homing and protects allografts without inducing general immunosuppression [J].

Brinkmann, V ;

Chen, S ;

Feng, L ;

Pinschewer, D ;

Nikolova, Z ;

Hof, R .

TRANSPLANTATION PROCEEDINGS, 2001, 33 (1-2) :530-531

[4] Human safety and pharmacology of FTY 720 [J].

Brunkhorst, R ;

Neumayer, HH ;

Hiss, M ;

Budde, K ;

Lucker, P ;

Mayer, T ;

Brookman, L ;

Schmouder, R .

TRANSPLANTATION, 1999, 67 (07) :S153-S153

[5] The identification of myriocin-binding proteins [J].

Chen, JK ;

Lane, WS ;

Schreiber, SL .

CHEMISTRY & BIOLOGY, 1999, 6 (04) :221-235

[6]

Chen SH, 2000, TRANSPLANTATION, V69, pS194

[7]

Chiba K, 1996, TRANSPLANT P, V28, P1056

[8]

Chiba K, 1998, J IMMUNOL, V160, P5037

[9] CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs [J].

Förster, R ;

Schubel, A ;

Breitfeld, D ;

Kremmer, E ;

Renner-Müller, I ;

Wolf, E ;

Lipp, M .

CELL, 1999, 99 (01) :23-33

[10] FTY720, a novel immunosuppressive agent with insulinotropic activity, prolongs graft survival in a mouse islet transplantation model [J].

Fu, F ;

Hu, S ;

Li, S ;

DeLeo, J ;

Hoover, J ;

Wang, S ;

Lake, P ;

Shi, V .

TRANSPLANTATION PROCEEDINGS, 2001, 33 (1-2) :672-673

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