Synthesis of 2-dienylindole, SB 242784, by a three-component palladium-catalyzed coupling reaction

被引：46

作者：

Yu, MS ^{[1
]}

de Leon, LL ^{[1
]}

McGuire, MA ^{[1
]}

Botha, G ^{[1
]}

机构：

[1] SmithKline Beecham Pharmaceut, King Of Prussia, PA 19403 USA

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 51期

关键词：

D O I：

10.1016/S0040-4039(98)02161-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：9347 / 9350

页数：4

共 17 条

[1] PALLADIUM-CATALYZED CYCLIZATION OF 2-ALKYNYLANILINES TO 2-SUBSTITUTED INDOLES UNDER AN ACIDIC 2-PHASE SYSTEM
CACCHI, S
CARNICELLI, V
MARINELLI, F
[J]. JOURNAL OF ORGANOMETALLIC CHEMISTRY, 1994, 475 (1-2) : 289 - 296
[2] SYNTHESIS AND PROPERTIES OF HALOHYDROXYACETONES AND HALOMETHYLGLYOXALS
CHARI, RVJ
KOZARICH, JW
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1982, 47 (12) : 2355 - 2358
[3] 5-(5,6-dichloro-2-indolyl)-2-methoxy-2,4-pentadienamides:: Novel and selective inhibitors of the vacuolar H+-ATPase of osteoclasts with bone antiresorptive activity
Gagliardi, S
Nadler, G
Consolandi, E
Parini, C
Morvan, M
Legave, MN
Belfiore, P
Zocchetti, A
Clarke, GD
James, I
Nambi, P
Gowen, M
Farina, C
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1998, 41 (10) : 1568 - 1573
[4] Hara S, 1996, SYNLETT, P993
[5] (E)-(2-BROMOETHENYL)DIISOPROPOXYBORANE - A NEW BUILDING BLOCK FOR (E)-OLEFINS
HYUGA, S
YAMASHINA, N
HARA, S
SUZUKI, A
[J]. CHEMISTRY LETTERS, 1988, (05) : 809 - 812
[6] ORGANIC-SYNTHESIS USING HALOBORATION REACTION .21. A SYNTHESIS OF PROSTAGLANDIN B-1 METHYL-ESTER BY THE STEPWISE CROSS-COUPLING REACTION USING (E)-(2-BROMOETHENYL)DIISOPROPOXYBORANE
HYUGA, S
HARA, S
SUZUKI, A
[J]. BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1992, 65 (08) : 2303 - 2305
[7] E-(3-TRIFLUOROMETHYL-1,3-BUTADIENYL)DI-ISOPROPOXYBORANE AS A POTENTIALLY USEFUL CF3-CONTAINING BUILDING-BLOCK - SYNTHESIS AND PALLADIUM-PROMOTED COUPLING WITH ARYL HALIDES
JIN, FQ
XU, YY
JIANG, B
[J]. JOURNAL OF FLUORINE CHEMISTRY, 1993, 65 (1-2) : 111 - 114
[8] A SIMPLE, GENERAL AND STEREOSELECTIVE SYNTHESIS OF 1-(DIALKOXYBORYL)-1,3-DIENES
MAZAL, C
VAULTIER, M
[J]. TETRAHEDRON LETTERS, 1994, 35 (19) : 3089 - 3090
[9] A SIMPLE AND ECONOMICAL SYNTHETIC ROUTE TO P-ETHYNYLANILINE AND ETHYNYL-TERMININATED SUBSTRATES
MELISSARIS, AP
LITT, MH
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1994, 59 (19) : 5818 - 5821
[10] NADLER G, 1998, UNPUB BIORG MED CHEM

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