Prediction of scattered dose to the testes in abdominopelvic radiotherapy

被引:28
作者
Budgell, GJ [1 ]
Cowan, RA [1 ]
Hounsell, AR [1 ]
机构
[1] Christie Hosp NHS Trust, Manchester M20 4BX, Lancs, England
关键词
fertility; radiotherapy; testes;
D O I
10.1053/clon.2001.9234
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Radical abdominal radiotherapy in men runs the risk of impairing their fertility owing to scattered dose to the testes, outside of the treated volume. In patients for whom this is a concern it is important to be able to predict the dose to the testes before treatment in order to determine whether semen cryopreservation should be undertaken and testicular shielding performed during treatment. Measurements have been made on an anthropomorphic phantom to determine the magnitude of these doses for a four-field treatment consisting of an anterior-posterior parallel pair and a lateral parallel pair. A dataset is presented, which, together with a correction for patient size, allows an estimate of testicular dose to be made given only the photon energy, interfield distances and the distance from the testes to the nearest beam edge. Thermoluminescent dosimetry has been carried out in 17 patients to validate the use of the data tables. The results indicate that testicular doses may be estimated with a standard deviation corresponding to 1%-2% of the tumour dose, which is sufficient for the purpose of determining whether fertility is threatened by a planned treatment.
引用
收藏
页码:120 / 125
页数:6
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