Potentiometric detection of thiols: a mechanistic evaluation of quinone-thiol interactions

被引：27

作者：

Digga, A

Gracheva, S

Livingstone, C

Davis, J ^{[1
]}

机构：

[1] Univ Surrey, Sch Biomed & Mol Sci, Dept Chem, Guildford GU2 7XH, Surrey, England

[2] Royal Surrey Cty Hosp, Guildford GU2 7XX, Surrey, England

来源：

ELECTROCHEMISTRY COMMUNICATIONS | 2003年 / 5卷 / 08期

关键词：

quinone; thiol; mechanism; potentiometry;

D O I：

10.1016/S1388-2481(03)00172-3

中图分类号：

O646 [电化学、电解、磁化学];

学科分类号：

081704 ;

摘要：

The potentiometric response resulting from the sequential addition of reduced thiols to a benzoquinone/hydroquinone couple has been investigated. The system has been shown to offer a simple route through which thiol could be quantified but a discrepancy in the reaction stoichiometry between glutathione and cysteine was observed. A mechanistic appraisal of the quinone-thiol interactions has been conducted and the proposed reaction pathways corroborated by spectroscopic analysis. (C) 2003 Published by Elsevier B.V.

引用

页码：732 / 736

页数：5

共 20 条

[11] Highly sensitive determination of acetylcholinesterase activity based on the chemisorption/reductive desorption-process of thiol compound on a silver electrode [J].