An ultrasensitive electrochemical biosensor for detection of DNA species related to oral cancer based on nuclease-assisted target recycling and amplification of DNAzyme

被引:102
作者
Chen, JingHua [1 ,2 ]
Zhang, Jing [1 ]
Guo, Yang [1 ]
Li, Juan [1 ]
Fu, FengFu [1 ]
Yang, Huang-Hao [1 ]
Chen, Guonan [1 ]
机构
[1] Fuzhou Univ, Fujian Prov Key Lab Anal & Detect Food Safety, Key Lab Anal & Detect Food Safety, Minist Educ, Fuzhou 350002, Fujian, Peoples R China
[2] Fujian Med Univ, Fac Pharm, Dept Pharmaceut Anal, Fuzhou 350004, Peoples R China
关键词
SIGNAL AMPLIFICATION; EXONUCLEASE; ELECTRODES;
D O I
10.1039/c1cc11929j
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A simple, label-free, ultra-highly sensitive and selective electrochemical sensor based on nuclease-assisted target recycling and DNAzyme for the detection of DNA species related to oral cancer in saliva is developed.
引用
收藏
页码:8004 / 8006
页数:3
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