Hydrophilic mesoporous carbon nanoparticles as carriers for sustained release of hydrophobic anti-cancer drugs

被引：108

作者：

Gu, Jinlou ^{[1
]}

Su, Shasha ^{[1
]}

Li, Yongsheng ^{[1
]}

He, Qianjun ^{[2
]}

Shi, Jianlin ^{[1
,2
]}

机构：

[1] E China Univ Sci & Technol, Sch Mat Sci & Engn, Key Lab Ultrafine Mat Minist Educ, Shanghai 200237, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 07期

关键词：

SILICA NANOPARTICLES; INTRACELLULAR DELIVERY; CYTOTOXICITY; SPHERES; WATER;

D O I：

10.1039/c0cc04598e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The uniform mesoporous carbon nanoparticles (MCNs) with size below 200 nm and good water dispersibility were successfully synthesized via a combined hydrothermal synthesis and hard templating. The prepared MCNs served as effective carriers for camptothecin which efficiently inhibited the growth of MCF-7 cancer cells after its sustained release therein.

引用

页码：2101 / 2103

页数：3

共 27 条

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