Specific Protein Detection Using Thermally Reduced Graphene Oxide Sheet Decorated with Gold Nanoparticle-Antibody Conjugates

被引：363

作者：

Mao, Shun ^{[1
]}

Lu, Ganhua ^{[1
]}

Yu, Kehan ^{[1
]}

Bo, Zheng ^{[1
]}

Chen, Junhong ^{[1
,2
,3
]}

机构：

[1] Univ Wisconsin, Dept Mech Engn, Milwaukee, WI 53211 USA

[2] Tongji Univ, Coll Environm Sci & Engn, State Key Lab Pollut Control & Resource Reuse, Shanghai 200092, Peoples R China

[3] Tongji Univ, Inst Adv Mat & Nano Biomed, Shanghai 200092, Peoples R China

来源：

ADVANCED MATERIALS | 2010年 / 22卷 / 32期

基金：

美国国家科学基金会;

关键词：

CARBON NANOTUBES; SELECTIVE DETECTION; DNA; ENHANCEMENT; SENSITIVITY; TRANSISTORS; BIOSENSORS; FILMS;

D O I：

10.1002/adma.201000520

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A highly sensitive and selective field-effect transistor biosensor using thermally reduced graphene oxide (TRGO) sheet decorated with gold nanoparticle-antibody conjugates is demonstrated. Probe antibody (anti-Immunoglobulin G) is labeled on the surface of the TRGO sheet through gold nanoparticles and electrical detection of the protein binding (Immunoglobulin G and anti-Immunoglobulin G) is accomplished by FET and dc measurements.

引用

页码：3521 / +

页数：7

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