Synthesis of aromatic aldehydes by organocatalytic [4+2] and [3+3] cycloaddition of α,β-unsaturated aldehydes

被引：78

作者：

Hong, Bor-Cherng ^{[1
]}

Tseng, Hsing-Chang ^{[1
]}

Chen, Shang-Hung ^{[1
]}

机构：

[1] Natl Chung Cheng Univ, Dept Chem & Biochem, Chiayi 621, Taiwan

来源：

TETRAHEDRON | 2007年 / 63卷 / 13期

关键词：

organocatalysis; proline; cycloaddition; unsaturated aldehyde;

D O I：

10.1016/j.tet.2007.01.039

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Organocatalytic inter- and intramolecular [4+2] and [3+3] cycloadditions of alpha,beta-unsaturated aldehydes to give polysubstituted aromatic aldehydes are described. High periselectivity for the cycloadditions, with catalyst effects exerted by L-proline and pyrrolidine-HOAc, as well as cocatalyst, additive effects, has been observed. (c) 2007 Elsevier Ltd. All rights reserved.

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页码：2840 / 2850

页数：11

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