Reaction between isocyanides and chalcones: an effcient solvent-free synthesis of 5-hydroxy-3,5-diaryl-1,5dihydro-2H-pyrrol-2-ones

被引：48

作者：

Adib, Mehdi ^{[1
]}

Mahdavi, Mohammad ^{[1
]}

Noghani, Mahsa Alizadeh ^{[1
]}

Bijanzadeh, Hamid Reza ^{[1
]}

机构：

[1] Univ Tehran, Univ Coll Sci, Sch Chem, Tehran, Iran

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 45期

关键词：

5-hydroxy-3,5-diaryl-1,5-dihydro-2H-pyrrol-2-ones; gamma-hydroxy-alpha-beta-unsaturated gamma-lactams; 1,3-diaryl-2-propen-1-ones; isocyanides; solvent-free synthesis;

D O I：

10.1016/j.tetlet.2007.09.030

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple and efficient synthesis of 5-hydroxy-3,5-diaryl-1,5-dihydro-2H-pyrrol-2-ones is described. Heating a mixture of an isocyanide and a 1,3-diaryl-2-propen-1-one under solvent-free conditions produces the title compounds in good to excellent yields. (C) 2007 Elsevier Ltd. All rights reserved.

引用

页码：8056 / 8059

页数：4

共 25 条

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