Applications of capillary electrophoresis on microchip

被引：94

作者：

Dolnik, V

Liu, SR

机构：

[1] Alcor BioSeparat, Santa Clara, CA 95051 USA

[2] Texas Tech Univ, Dept Chem & Biochem, Lubbock, TX USA

来源：

JOURNAL OF SEPARATION SCIENCE | 2005年 / 28卷 / 15期

关键词：

capillary electrophoresis; CZE; isoelectric focusing; microchip; review;

D O I：

10.1002/jssc.200500243

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

CE on microchip is an emerging separation technique that has attracted wide attention and gained considerable popularity. Because of miniaturization of the separation format, CIE on chip typically offers shorter analysis time and lower reagent consumption with potential development of portable analytical instrumentation. This review with 143 references is focused on proteins and peptides analysis, DNA separation including fragment sizing, genotyping, mutation detection and sequencing, and also the analysis of low-molecular-weight compounds, namely explosive residues and warfare agents, pharmaceuticals and drugs of abuse, and various small molecules in body fluids.

引用

页码：1994 / 2009

页数：16

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