Carbon nanotube coating improves neuronal recordings

被引:543
作者
Keefer, Edward W. [1 ]
Botterman, Barry R. [2 ]
Romero, Mario I. [1 ,3 ]
Rossi, Andrew F. [4 ]
Gross, Guenter W. [5 ]
机构
[1] UTSW Med Sch, Dept Plast Surg, Dallas, TX 75390 USA
[2] UTSW Med Sch, Dept Cell Biol, Dallas, TX 75390 USA
[3] Texas Scottish Rite Hosp Children, Dallas, TX 75219 USA
[4] Vanderbilt Univ, Dept Psychol, Nashville, TN 37203 USA
[5] Univ N Texas, Dept Biol, Denton, TX 76203 USA
关键词
D O I
10.1038/nnano.2008.174
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Implanting electrical devices in the nervous system to treat neural diseases is becoming very common. The success of these brain-machine interfaces depends on the electrodes that come into contact with the neural tissue. Here we show that conventional tungsten and stainless steel wire electrodes can be coated with carbon nanotubes using electrochemical techniques under ambient conditions. The carbon nanotube coating enhanced both recording and electrical stimulation of neurons in culture, rats and monkeys by decreasing the electrode impedance and increasing charge transfer. Carbon nanotube-coated electrodes are expected to improve current electrophysiological techniques and to facilitate the development of long-lasting brain-machine interface devices.
引用
收藏
页码:434 / 439
页数:6
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