The SCOP database in 2020: expanded classification of representative family and superfamily domains of known protein structures

被引:207
作者
Andreeva, Antonina [1 ]
Kulesha, Eugene [2 ]
Gough, Julian [1 ]
Murzin, Alexey G. [1 ]
机构
[1] MRC Lab Mol Biol, Francis Crick Ave, Cambridge CB2 0QH, England
[2] EKMM Ltd, Cambridge CB1 9AZ, England
基金
英国生物技术与生命科学研究理事会; 英国医学研究理事会;
关键词
SEQUENCES;
D O I
10.1093/nar/gkz1064
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The Structural Classification of Proteins (SCOP) database is a classification of protein domains organised according to their evolutionary and structural relationships. We report a major effort to increase the coverage of structural data, aiming to provide classification of almost all domain super-families with representatives in the PDB. We have also improved the database schema, provided a new API and modernised the web interface. This is by far the most significant update in coverage since SCOP 1.75 and builds on the advances in schema from the SCOP 2 prototype.
引用
收藏
页码:D376 / D382
页数:7
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