Solutions for library encoding to create collections of discrete compounds

被引:30
作者
Affleck, RL [1 ]
机构
[1] Discovery Partners Int, San Diego, CA 92121 USA
关键词
D O I
10.1016/S1367-5931(00)00200-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The ability to design, produce, analyze, and manage high quality combinatorial libraries depends on the encoding strategy applied. Several recent advances in encoding technology have extended the range of library design parameters. Enhancements of established techniques have made them more robust and versatile, while additional new and creative encoding concepts have been introduced. With better options now available, combinatorial chemists can more easily select an encoding technique to match resources, library design, and compound management criteria.
引用
收藏
页码:257 / 263
页数:7
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