Electrophoretic separations on microfluidic chips

被引：145

作者：

Wu, Dapeng ^{[1
]}

Qin, Jianhua ^{[1
]}

Lin, Bingcheng ^{[1
]}

机构：

[1] Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China

来源：

JOURNAL OF CHROMATOGRAPHY A | 2008年 / 1184卷 / 1-2期

基金：

中国国家自然科学基金;

关键词：

microchip electrophoresis; injection; turn; joule heating; surface modification; concentration; DNA; protein; amino acids;

D O I：

10.1016/j.chroma.2007.11.119

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

This review presents a brief outline and novel developments of electrophoretic separation in microfluidic chips. Distinct characteristics of microchip electrophoresis (MCE) are discussed first, in which sample injection plug, joule heat, channel turn, surface adsorption and modification are introduced, and some successful strategies and recognized conclusions are also included. Important achievements of microfluidic electrophoresis separation in small molecules, DNA and protein are then summarized. This review is aimed at researchers, who are interested in MCE and want to adopt MCE as a functional unit in their integrated microsystems. (c) 2008 Elsevier B.V. All rights reserved.

引用

页码：542 / 559

页数：18

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