Integrative systems biology: an attempt to describe a simple weed

被引:25
作者
Liberman, Louisa M.
Sozzani, Rosangela
Benfey, Philip N. [1 ]
机构
[1] Duke Univ, Dept Biol, Durham, NC 27706 USA
关键词
GENE-EXPRESSION MAP; METABOLIC PATHWAYS; PLANT METABOLOMICS; ARABIDOPSIS ROOTS; GLOBAL RESPONSES; DATA SETS; PROTEOME; REVEALS; TRANSCRIPTOME; TOOL;
D O I
10.1016/j.pbi.2012.01.004
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Genome-scale studies hold great promise for revealing novel plant biology. Because of the complexity of these techniques, numerous considerations need to be made before embarking on a study. Here we focus on the Arabidopsis model system because of the wealth of available genome-scale data. Many approaches are available that provide genome-scale information regarding the state of a given organism (e.g. genomics, epigenomics, transcriptomics, proteomics, metabolomics interactomics, ionomics, phenomics, etc.). Integration of all of these types of data will be necessary for a comprehensive description of Arabidopsis. In this review we propose that 'triangulation' among transcriptomics, proteomics and metabolomics is a meaningful approach for beginning this integrative analysis and uncovering a systems level perspective of Arabidopsis biology.
引用
收藏
页码:162 / 167
页数:6
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