Efficient synthesis of optically active β-hydroxy p-tolylsulfones with very high enantiomeric excess via CBS-oxazaborolidine-catalyzed borane reduction

被引：41

作者：

Cho, BT ^{[1
]}

Kim, DJ ^{[1
]}

机构：

[1] Hallym Univ, Dept Chem, Chunchon 200702, South Korea

来源：

TETRAHEDRON-ASYMMETRY | 2001年 / 12卷 / 14期

关键词：

D O I：

10.1016/S0957-4166(01)00359-7

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A simple, efficient synthesis of optically active beta -hydroxy p-tolylsulfones with > 99% e.e. by employing CBS oxazaboronlidene-catalyzed asymmetric borane reduction of beta -keto p-tolylsulfones using N-ethyl-N-iso-propylaniline-borane complex as the borane carrier has been established. (C) 2001 Elsevier Science Ltd. All rights reserved.

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页码：2043 / 2047

页数：5

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