Chromosome chains and platypus sex: kinky connections

被引：8

作者：

Ashley, T ^{[1
]}

机构：

[1] Yale Univ, Sch Med, Dept Genet, New Haven, CT 06510 USA

来源：

BIOESSAYS | 2005年 / 27卷 / 07期

关键词：

D O I：

10.1002/bies.20265

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Mammal sex determination depends on an XY chromosome system, a gene for testis development and a means of activating the X chromosome. The duckbill platypus challenges these dogmas. ((1,2)) Gutzner et al. ((1)) find no recognizable SRY sequence and question whether the mammalian X was even the original sex chromosome in the platypus. Instead they suggest that the original platypus sex chromosomes were derived from the ZW chromosome system of birds and reptiles. Unraveling the puzzles of sex determination and dosage compensation in the platypus has been complicated by the fact that it has a surplus of sex chromosomes. Rather than a single X and Y chromosome, the male platypus has five Xs and fiveYs. (c) 2005 Wiley Periodicals, Inc.

引用

页码：681 / 684

页数：4

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