Catalytic, asymmetric synthesis of siphonarienal

被引：43

作者：

Calter, MA ^{[1
]}

Liao, WS ^{[1
]}

Struss, JA ^{[1
]}

机构：

[1] Univ Rochester, Dept Chem, Rochester, NY 14627 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2001年 / 66卷 / 22期

关键词：

D O I：

10.1021/jo0160367

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This paper describes the synthesis of the marine natural product, siphonarienal. The key step of this synthesis is an aldol reaction that constructs most of the skeleton and sets all three stereocenters of the target in one step from commercially available starting materials. Deoxygenation and chain homologation steps complete the synthesis.

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收藏

页码：7500 / 7504

页数：5

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