How do dendrites take their shape?

被引：232

作者：

Scott, EK

Luo, LQ ^{[1
]}

机构：

[1] Stanford Univ, Dept Biol Sci, Stanford, CA 94305 USA

[2] Stanford Univ, Neurosci Program, Stanford, CA 94305 USA

来源：

NATURE NEUROSCIENCE | 2001年 / 4卷 / 04期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1038/86006

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Recent technical advances have made possible the visualization and genetic manipulation of individual dendritic trees. These studies have led to the identification and characterization of molecules that are important for different aspects of dendritic development. Although much remains to be learned, the existing knowledge has allowed us to take initial steps toward a comprehensive understanding of how complex dendritic trees are built. In this review, we describe recent advances in our understanding of the molecular mechanisms underlying dendritic morphogenesis, and discuss their cell-biological implications.

引用

页码：359 / 365

页数：7

共 102 条

[31] kakapo, a gene required for adhesion between and within cell layers in Drosophila, encodes a large cytoskeletal linker protein related to plectin and dystrophin [J].