The polyol domain of amphidinol 3. A stereoselective synthesis of the entire C(1)-C(30) sector

被引：51

作者：

Paquette, LA ^{[1
]}

Chang, SK ^{[1
]}

机构：

[1] Ohio State Univ, Evans Chem Labs, Columbus, OH 43210 USA

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 14期

关键词：

D O I：

10.1021/ol0511833

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The richly oxygenated C(1)-C(30) polyol segment of amphidinol 3 has been synthesized in protected form. Incorporated in this long chain are 10 of the 25 stereogenic centers housed in the target. The asymmetric pathway that has been developed is based on the efficient union of three independently prepared subunits.

引用

页码：3111 / 3114

页数：4

共 14 条

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