Asymmetric catalytic addition of diorganozinc reagents to imines:: Scope and application

被引：34

作者：

Charette, AB ^{[1
]}

Boezio, AA ^{[1
]}

Côté, A ^{[1
]}

Moreau, E ^{[1
]}

Pytkowicz, J ^{[1
]}

Desrosiers, JN ^{[1
]}

Legault, C ^{[1
]}

机构：

[1] Univ Montreal, Dept Chim, Montreal, PQ H3C 3J7, Canada

来源：

PURE AND APPLIED CHEMISTRY | 2005年 / 77卷 / 07期

关键词：

asymmetry; enantioselectivity; catalysis; copper; redox; sulfinate; diorganozinc; BozPHOS; alpha-chiral amines; phosphinoylimine;

D O I：

10.1351/pac200577071259

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The copper-catalyzed diorganozinc addition to N-diphenylphosphinoylimines was shown to proceed with a very high degree of enantiocontrol if the reaction was run in the presence of Me-DuPHOS monoxide ligand (BozPHOS). The scope of the reaction is described as well as our efforts to identify the nature of the enantioactive metal complex responsible for the high asymmetric induction.

引用

页码：1259 / 1267

页数：9

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