Direct, highly enantioselective pyrrolidine sulfonamide catalyzed Michael addition of aldehydes to nitrostyrenes

被引：362

作者：

Wang, W ^{[1
]}

Wang, J ^{[1
]}

Li, H ^{[1
]}

机构：

[1] Univ New Mexico, Dept Chem, Albuquerque, NM 87131 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 09期

关键词：

aldehydes; asymmetric catalysis; Michael addition; nitroalkenes; organocatalysts;

D O I：

10.1002/anie.200461959

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Just can't get enough: The highly versatile pyrrolidine sulfonamide organocatalyst 1, which has been used in α-aminoxylation and Mannich-type reactions, also mediates diastereo- and enantioselective Michael addition reactions of aldehydes and ketones to nitroolefins (see scheme). © 2005 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：1369 / 1371

页数：3

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