A comparison of multileaf collimator with conformal blocks for the boost phase of dose-escalated conformal prostate radiotherapy

被引:7
作者
Bedford, JL
Khoo, VS
Warrington, AP
Bidmead, AM
Webb, S
Deamaley, DP
机构
[1] Inst Canc Res, Joint Dept Phys, Sutton SM2 5PT, Surrey, England
[2] Royal Marsden NHS Trust, Sutton SM2 5PT, Surrey, England
[3] Inst Canc Res, Acad Dept Radiotherapy & Oncol, Sutton SM2 5PT, Surrey, England
[4] Inst Canc Res, Joint Dept Phys, London SW3 6JJ, England
[5] Royal Marsden NHS Trust, London SW3 6JJ, England
关键词
conformal radiotherapy; dose escalation; prostate cancer; rectum; multileaf collimator; conformal block;
D O I
10.1016/S0167-8140(00)00314-5
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
A multileaf collimator (MLC) is compared with conformal blocks for delivering the boost phase of dose-escalated conformal prostate radiotherapy. When using conformal blocks, the volume of rectum irradiated to 90% (V-90) is lower (1.4 +/- 1.3%, 1 SD) for a three-field plan with gantry angles 0 degrees, 90 degrees, 270 degrees than for a six-held plan with gantry angles 50 degrees, 90 degrees, 130 degrees, 230 degrees, 270 degrees, 310 degrees (2.1 +/- 1.3%, P = 0.002). However, when using an MLC in which the leaves and wedge are oriented at right angles, V-90 is higher (4.7 +/- 3.0%) for a three-field plan than for a six-field plan (2.7 +/- 1.6%, P = 0.05). The larger increase in V-90 for the three-field plan when changing from conformal blocks to MLC is mainly due to the limitation imposed upon the MLC orientation by the use of wedges. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:45 / 50
页数:6
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