Excitatory effects of GABA in established brain networks

被引:98
作者
Marty, A [1 ]
Llano, I [1 ]
机构
[1] Univ Paris 05, Lab Physiol Cerebrale, F-75006 Paris, France
关键词
D O I
10.1016/j.tins.2005.04.003
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Although GABA remains the predominant inhibitory neurotransmitter of the brain, there are numerous recent examples of excitatory actions of GABA. These actions can be classified in two broad categories: phasic excitatory effects, as follow single activation of GABAergic afferents, and sustained excitatory effects, as follow prolonged activation of GABA(A) receptors. Evidence reviewed here indicates that, contrary to common belief, these effects are not restricted to embryonic or neonatal preparations.
引用
收藏
页码:284 / 289
页数:6
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