Human DNA repair genes, 2005

被引：344

作者：

Wood, RD

Mitchell, M

Lindahl, T

机构：

[1] Univ Pittsburgh, Inst Canc, Hillman Canc Ctr, Pittsburgh, PA 15213 USA

[2] Canc Res UK, London Res Inst, Lincolns Inn Fields Labs, London WC2 3PX, England

[3] Canc Res UK, London Res Inst, Clare Hall Labs, S Mimms EN6 3LD, Herts, England

来源：

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS | 2005年 / 577卷 / 1-2期

关键词：

DNA; base excision repair; nucleotide excision repair; DNA repair gene; damage response genes; replication forks;

D O I：

10.1016/j.mrfmmm.2005.03.007

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

An updated inventory of about 150 human DNA repair genes is described. The compilation includes genes encoding DNA repair enzymes, some genes associated with cellular responses to DNA damage, and other genes associated with genetic instability or sensitivity to DNA damaging agents. The updated human DNA repair genes table (http://www.cgal.icnet.uk/DNA-Repair-Genes.html) is a research and reference tool that directly links to several databases: Gene Cards, Online Mendelian Inheritance in Man, the NCBI MapViewer for chromosome position, and the NCBI Entrez database for the reference nucleotide sequence. This article discusses the approximately 25 genes added, since the original version of the table was first produced in 2001, and some other revisions. (C) 2005 Elsevier B.V. All rights reserved.

引用

页码：275 / 283

页数：9

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