New skeletal rearrangements of C and D rings of a 13-oxobaccatin III derivative

被引：9

作者：

Marder-Karsenti, R ^{[1
]}

Dubois, J ^{[1
]}

Chiaroni, A ^{[1
]}

Riche, C ^{[1
]}

Guénard, D ^{[1
]}

Guéritte, F ^{[1
]}

Potier, P ^{[1
]}

机构：

[1] CNRS, Inst Chim Subst Nat, F-91198 Gif Sur Yvette, France

来源：

TETRAHEDRON | 1998年 / 54卷 / 52期

关键词：

D O I：

10.1016/S0040-4020(98)00993-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

13-Oxobaccatin III (4) was oxidized to 7,13-dioxo D-secobaccatin III (5). This compound, when treated with base or cyanide ion, underwent rearrangements involving the rupture of the C-7,C-8 bond, the migration of the benzoyl and acetyl groups and intramolecular formation of new rings. Four new compounds were isolated and fully characterized. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：15833 / 15844

页数：12

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