Pathogenicity islands and virulence evolution in Listeria

被引：173

作者：

Vázquez-Boland, JA

Domínguez-Bernal, G

González-Zorn, B

Kreft, J

Goebel, W

机构：

[1] Univ Complutense Madrid, Fac Vet, Grp Patogenesis Mol Bacteriana, Unidad Microbiol & Inmunol,Dept Patol Anim 1, E-28040 Madrid, Spain

[2] Univ Wurzburg, Lehrstuhl Mikrobiol, Biozentrum, D-97074 Wurzburg, Germany

来源：

MICROBES AND INFECTION | 2001年 / 3卷 / 07期

关键词：

Listeria; Listeria monocytogenes; Listeria innocua; Listeria ivanovii; pathogenicity islands; LIPI-1; LIPI-2; LRR proteins; virulence evolution; microbial pathogenesis;

D O I：

10.1016/S1286-4579(01)01413-7

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

As in other bacterial pathogens, the virulence determinants of Listeria species are clustered in genomic islands scattered along the chromosome. This review summarizes current knowledge about the structure, distribution and role in pathogenesis of Listeria virulence loci. Hypotheses about the mode of acquisition and evolution of these loci in this group of Gram-positive bacteria are presented and discussed. (C) 2001 Editions scientifiques et medicales Elsevier SAS.

引用

页码：571 / 584

页数：14

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