Diagnosing Autism Spectrum Disorders in Adults: the Use of Autism Diagnostic Observation Schedule (ADOS) Module 4

被引:145
作者
Bastiaansen, Jojanneke A. [1 ,2 ]
Meffert, Harma [1 ,3 ]
Hein, Simone [2 ]
Huizinga, Petra [2 ]
Ketelaars, Cees [4 ]
Pijnenborg, Marieke [6 ]
Bartels, Arnold [3 ]
Minderaa, Ruud [5 ]
Keysers, Christian [1 ,7 ]
de Bildt, Annelies [5 ]
机构
[1] Univ Med Ctr Groningen, Dept Neurosci, Social Brain Lab, NL-9700 RB Groningen, Netherlands
[2] Lentis, Autism Team N Netherlands, NL-9728 JR Groningen, Netherlands
[3] Forint, FPC Dr S van Mesdag, NL-9722 AZ Groningen, Netherlands
[4] Dimence, Jeugd & Autisme, NL-8021 EV Zwolle, Netherlands
[5] Univ Groningen, Univ Med Ctr Groningen, Dept Psychiat, NL-9700 RB Groningen, Netherlands
[6] GGZ Drenthe, Psychosencluster, NL-9404 LA Assen, Netherlands
[7] Royal Netherlands Acad Arts & Sci KNAW, Netherlands Inst Neurosci, Social Brain Lab, NL-1105 BA Amsterdam, Netherlands
关键词
Autism; Adults; ADOS; Diagnosis; Schizophrenia; Psychopathy; HIGH-FUNCTIONING AUTISM; ADOLESCENTS; SYMPTOMS; CHILDREN; SCHIZOPHRENIA; EPIDEMIOLOGY; BEHAVIORS; LANGUAGE; EMPATHY;
D O I
10.1007/s10803-010-1157-x
中图分类号
B844 [发展心理学(人类心理学)];
学科分类号
040202 ;
摘要
Autism Diagnostic Observation Schedule (ADOS) module 4 was investigated in an independent sample of high-functioning adult males with an autism spectrum disorder (ASD) compared to three specific diagnostic groups: schizophrenia, psychopathy, and typical development. ADOS module 4 proves to be a reliable instrument with good predictive value. It can adequately discriminate ASD from psychopathy and typical development, but is less specific with respect to schizophrenia due to behavioral overlap between autistic and negative symptoms. However, these groups differ on some core items and explorative analyses indicate that a revision of the algorithm in line with Gotham et al. (J Autism Dev Disord 37: 613-627, 2007) could be beneficial for discriminating ASD from schizophrenia.
引用
收藏
页码:1256 / 1266
页数:11
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